Endocrine Abstracts

64 year old male with known hypertension presented with fatigue and mild vertigo to the emergency department. Blood pressure was 110/65 mmHg. Physical examination revealed bilateral inspratory crackles with bilateral pedal oedema. There was not any skin discolourisation or bruises. Patient history indicated a suspected lung malignancy but pathological diagnosis was yet to be concluded. Laboratury test showed that sodium level was 117 mEq/l, potassium level was 5.2 mEq/l, venou...

A 52 year old lady presented with a six month history of weight loss and fatigue. Physical examination showed mild abdominal discomfort on the right flank with signs of anemia. Blood pressure was 130/60 mmHg, pulse was 83 bpm regular. Tender goitre or tremor were not present. Laboratory tests revealed tsh: 0.008 mUI/l (0.37-4.45), fT4: 2.12 ng/dl (0.8-1.8), thyroglobulin 40 ng/ml (5-42), TPO-Ab <35 IU/ml and TgAb <20 IU/ml, sedimentation:72 mm/h, crp: 59 mg/dl with nor...

Introduction: Wegener granulomatosis is a necrotizing granulomatous small-vessel vasculitis. It typically affects the upper respiratory tract, lungs, and kidneys but can involve virtually any organ including the pituitary. Pituitary involvement in wegener granumatosis is rare.Case: A 50-year-old woman was admitted to the hospital with severe dyspne for 2 years and stridor for a month. During her hospitalization, her sodium level was noted to be persisten...

Background: Suture granuloma, the rare complication of thyroidectomy, results from use of nonabsorbable suture materials. Despite its typical ultrasound images and benign course, it carries utmost importance in differential diagnosis of lymph nodes, recurrent nodules, and recurrence in case of thyroid cancers.Case report: A 54-year-old female patient, who underwent bilateral thyroidectomy in July 2010, was diagnosed with multinodular goiter and incidenta...

Introduction: The coexistence of hyperthyroidism and thyroid cancer is considered a rare event. We describe a case of papillary carcinoma of the thyroid that mimicked a diffuse toxic goiter.Case report: A 26-year-old female patient presented with a complaint of malaise was diagnosed to have thyrotoxicosis and following the tests performed (sT3: 7.7 (1.7–3.7 ng/dl), sT4: 2.5 (0.7–1.49 ng/dl) TSH: <0.0025 (0.35–4.94...

Aims: In this study, we examined the relationships between levels of adipocytokines and traditional and non-traditional cardiovascular risk markers in patients with type 2 diabetes mellitus (T2DM).Methods: Serum leptin, resistin, adiponectin, visfatin, high sensitive C-reactive protein (hsCRP), homocystein, asymetric dimethylarginine (ADMA), fasting glucose, insulin, glycated haemoglobin (HbA1C) and full lipid and lipoprotein profile, systolic...

Introduction: The frequency of new-onset diabetes after transplant (NODAT) is 5–30% in liver transplant recipients. We aimed to analyze the frequency and predictors of NODAT in the patients undergoing liver transplantation (LTx) due to acute liver failure(ALF), and to investigate whether pretransplant hypoglycemia had any effect on NODAT.Materials and methods: Adult patients undergoing LTx due to ALF were analyzed retrospectively. The patients with...

Aim: Thyroid papillary carcinomas smaller than 1 cm are called papillary microcarcinomas (PMC). They rarely metastasize to lymph node (LN) and distant areas. The presence of palpable lymphadenopathy at the time of diagnosis shows high risk of recurrence regardless of primary tumor size. We aimed to investigate histopathologic characteristics and recurrence frequency of thyroid PMCs with LN metastasis (LNM).Materials and methods: Thyroid PMC cases with LN...

Introduction: Osteogenesis imperfecta (OI) is a congenital, generalized connective tissue disorder characterized by severe osteoporosis and bone fragility. OI is most commonly caused by mutations in genes encoding the α-1 and α-2 chains of type I collagen or proteins involved in posttranslational modification of type I collagen. Although, no controlled studies are done, bisphosphonates are used for the treatment of OI. I.v. bisphosphonates are reported to be more eff...

Introduction: Adrenocortical carcinoma (ACC) is a rare cancer (estimated incidence, 0.7 to 2.0 cases per 1 million population per year) with a poor prognosis. Even after seemingly complete surgical resection, most patients develop recurrence within 5 years. The 5-year survival rate is <15% among patients with metastatic disease.Methods: We present the results of six patients with adrenocortical carcinoma followed in our clinic....